Yearly prophylactic injections of corticosteroids aren't recommended for routine allergic conditions. These depot steroids have been associated with profound and long-lasting HPA suppression. They were originally advised (rarely) for the hard-to-control patient with life- threatening asthma who abused medications or was noncompliant. Today there's a much wider selection of inhaled and oral preparations, with easier dosing regimens, than were available when depot steroids first came into use.