This quiz is just for fun. Test your diagnostic skills with the photos, then separate truth from fiction in the statements about psoriasis and cephalosporins. Any of the statements below might be true… and any might just be us pulling your leg. Answers are below.

Psoriasis
2. Calcipotriol
True or False
a) is applied twice daily to plaques on the body or face
b) should not be combined with steroids
c) should not be used in patients with plaques covering more than 50% of the body surface
d) generally takes at least a month to show an effect
e) will cause skin atrophy if used long-term
f) in large doses, can upset calcium metabolism
3. Cephalosporins
True or False
a) should never be given to patients with penicillin allergy
b) should not be taken with food
c) must be given in lower doses when renal function is impaired
d) third generation cephalosporins are widely used in meningitis empiric therapy
e) some types can cause an acute sensitivity to alcohol, similar to the drug disulfiram
f) can cause a highly pruritic morbiliform rash if wrongly given in mononucleosis
1. Penile colonies: a)8 Scabies; b)3 Gonorrhea; c)4 Chlamydia; d)9 Peyronie’s disease; e)10 Zoon’s balanitis; f)2 Herpes simplex type 2; g)1Genital warts (HPV); h)5 Chancroid (Haemophilus ducreyi); i)7 Tinea cruris; j)6 Candida balanitis.
2. Calcipotriol: a) False. It’s applied twice daily, but not on the face; b) False. It’s often combined with betamethasone and a pre-mixed formulation is on the market; c) True, it should not be used in patients with plaques covering more than 50% of the body surface; d) False. Calcipotriol usually shows some effect within 2 weeks; e) False. This is a steroid effect; f) True, if over 100 g/week is used.
3. Cephalosporins: a) False. The proportion of penicillin-allergic patients who will have a hypersensitivity reaction to cephalosporins is often given as 10%, but this rests on data using the earliest 1st generation cephalosporins, and rates with later drugs are believed to be much lower; b) False. Older cephalosporins are well absorbed in presence of food, while food actually increases absorption of newer types; c) True; d) True, although 4th generation cephalosporins are better at crossing the blood-brain barrier; e) True, including latamoxef, cefmenoxime, moxalactam, cefoperazone, cefamandole, cefmetazole, and cefotetan. These drugs can also inhibit clotting; f) True, like all beta-lactam antibiotics.
We'll send you $100 if we print your diagnostic challenge. Send case description (app. 450 words) with final diagnosis and outcome to: parkex@parkpub.com.