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The clinical presentation is consistent with leprosy. Patients
typically exhibit at least 2 of the following cardinal signs:
- a skin lesion with sensory loss
- thickened peripheral nerves
- acid-fast bacilli on skin smears or tissue biopsy
In a deep skin biopsy (down to the fat) of one of Mr. T.J. s skin
lesions, no acid-fast bacilli were detected. The dermis, however,
showed granulomatous infiltration and, most importantly, involvement
of a cutaneous nerve. The biopsy was compatible with the clinical
diagnosis of borderline-tuberculoid leprosy, in which cellular immunity
is high but acid-fast bacilli are very scarce. Multidrug therapy
was initiated with daily rifampin and dapsone for 6 months. Mr.
T.J. was counselled to inspect his hands daily to detect injury
to his anesthetic fingers. Also, he was forced to start alternate
duties at work.
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