Diagnostic Challenge
Ironic reflections There's more to this case than just an abdominal aortic aneurysm. Can you spot the diagnosis?

Skin Sense
Pigmented purpura Leaking capillaries are behind these cayenne pepper-like spots.

Checklist
Torsade de pointes Be cautious when prescribing drugs that can induce this form of arrhythmia.

Update
Seizure disorders A look at the multiple causes and presentations of this common neurologic disturbance. By Kerri L. Schellenberg, MD and S. Nizam Ahmed, MD

Letters and Exchanges: what your colleagues are saying...
An interesting statistical reason why one reader doesn't want a shot at the U.S. presidency.

Mind Matters
The mid-life crisis They're not the beginning of the end, though the middle years may require an adjustment for some.

Perspectives on Pain
Trigeminal neuralgia A range of treatment options offers hope for patients who live with intense facial pain.

Cover photo: Amoeba (Hartmannella vermiformis) capturing a Legionella pneumophila bacterium; ©BSIP/CDC/Alpha Presse

Heart Beat
The waning vim on vitamins Study after study confirms that antioxidant supplements aren't a magic bullet to better cardiovascular health.

Food for Thought
In defence of soy New research on breast cancer risk shows why this protein-rich bean shouldn't get a bad rap.

Parkhurst correspondence
21 answers to your clinical questions Our panel answers your questions on serotonin syndrome, preventing Legionnaire's disease, watermelon allergy, and more…
Question authority Got a burning clinical question? Send it in and our experts will get you the best possible answer.
Question of the month Angioedema: how to best assess and treat

Tales from the Heart NEW COLUMN!
A case of mixed signals On a rainy day, a "flashing" moment nearly leads to a misunderstanding.

The art gallery
Dr. Mohamed Hirji exploits his visual nature whether he's studying an MRI or planning his next painting.
Marie Finkelstein trained as a lawyer, but now can't imagine life without painting what she sees and feels.

Meet the artists
Two Canadian artists feature their work in the Parkhurst Exchange gallery. Have a favourite artist or two? Kindly send their names to katz@parkpub.com and we may feature them too