Diagnostic Challenge
Rash reaction What's causing a stubborn itch that's resisting medication?

Casebook
Hyponatremia The search is on for what's causing increased antidiuretic hormone activity.

ClinicalTalk
Acute coronary syndrome part 2 Treatment for this cluster of diseases can be a race to beat the clock. An interview with Matthew Bennett, MD and Andrew Ignaszewski, MD

Update
Pancreaticobiliary disorders A review of clinical scenarios involving the digestive system. By Arni Sekar, MD

Letters and Exchanges: what your colleagues are saying...
Haven't entered our contests yet? These readers are glad they did.

Mind Matters
The highs and lows of self-esteem A look at what makes people feel good - or bad - about themselves.

Cultural Medicine
Hepatitis B and C Despite long odds, the debilitating effects of these diseases linger.

Heart Beat
A prompt prescription An urgent need for therapy is crucial with congestive heart failure.

Geriatrics
End-of-life planning Part 1 A legal eagle points out the particulars of wills.

Cover photo: Sarcoptes scabiei; ©Meullemiestre/BSIP/Alpha Presse

Food for Thought
Low-fat failure Our nutrition expert reviews the disappointing new data on diet and breast cancer risk.

The Compliance Factor
Hot flashes Defy these symptoms with conventional and alternative approaches to treatment.

From the front lines
Cod liver oil in pregnancy smells fishy, menopause meets mood swings, pain in tots, and more…

Parkhurst correspondence
24 answers to your clinical questions Our panel answers your questions on frozen shoulders, prescribing NSAIDs in renal disease patients, treating painful MS, and others…
This month's dermatology highlight The dark side of acanthosis nigricans.
Question of the month Are brain aneurysms a family affair?
Question authority When you'd like a second opinion, turn to our panel of experts for theirs.

Checklist
Short QT syndrome Novel genetic disease could lead to sudden cardiac death.

Skin Sense
Hemangiomas An overview of these common, but benign, birthmarks.

Journal Club
Leading experts comment on a treatment for knee osteoarthritis, antihypertensives and Alzheimer's disease, and risk factors for meningitis in teens.