question and answer
Is it risky to combine childhood immunizations?
March 2004
"More parents are questioning the increasing types of immunizations recommended for their children and the number given at any one visit. This concern is being fuelled by a revolt against combination injections in Europe," writes ALAN L. RUSSELL, MD, of Brampton, ON. He then asks, "What's the current evidence-based medical views on immunization risk, combination antigens and the possibility of viral interactions?"
Combination vaccines are approved for use only if studies demonstrate that it has comparable immunogenicity to each of the individual components of the vaccine and that overall side effects aren't greater than the most reactive single part. To date, there's no evidence to suggest that the currently approved combination vaccines are clinically inferior or associated with higher complication rates than the individual ones. KL
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