Complex regional pain syndrome consists of pain associated with sensory and vasomotor changes. In type I (reflex sympathetic dystrophy) there’s a nerve lesion. In type II (causalgia), there’s no clear nerve damage. Most cases start after an injury or other focal insult. Possible risk factors have included a history of headaches, smoking, osteoporosis, menstrual disorders and neuropathies. Some reports have suggested familial clustering of the disorder.

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